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M. UMAR FAROOQ, SALMAN MUTIULLAH SHAIKH, MAHBOOB AFZAL JAWAID, ARSALAN AHMED

ABSTRACT | Full Text PDF

OBJECTIVES: 1. To determine the presenting complaints of nasopharyngeal carcinoma. 2. To evaluate the skull base & cranial involvement by CT scan at the time of presentation.

STUDY DESIGN: Descriptive study.

SETTING: E.N.T department, DUHS & Civil Hospital Karachi

METHODS: From March 2007 to February 2009 (02 years), 19 patients of histologically proven nasopharyngeal carcinoma were selected for study. Demographic data, clinical and CT scan findings of the patients were recorded on purposely designed proforma. Statistical analysis carried out using SPSS, version 10.

RESULTS: Out of 19 patients, 15 male and 04 female (Ratio 3.75:1), mean age was 42.05 years ± 16.63. The most common presenting complaint was Neck swelling 78.9%, followed by audiological complaints 57.9%, nasal complaints 68.4%, epistaxis 42.10%, and neurological symptoms 47.36%. On CT scan 31.5% patients had Skull base erosion, 21% had bilateral multiple lymphadenopathy and 15.8% had intracranial involvement.

CONCLUSION: Nasopharyngeal carcinoma is an infrequent tumor. Presentation of the nasopharyngeal carcinoma is variable. Majority of the cases presented with neck mass, nasal, otological, and neurological features. Usually NPC presents at advance stage, highlighting the need to create awareness in public and health professionals.

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