Posted in Volume 15 - Number 4
MUHAMMAD ARIF BALOCH, SALEEM AHMED KHARAL, MUHAMMAD ASIF DURRANI, SHAFQAT QAMAR
ABSTRACT | Full Text PDF
OBJECTIVE: Catheter related bacteremia is a major cause of morbidity and mortality among patients on haemodialysis. Bacterial infection of all types seems to be increased in incidence, but there is a particular risk of infections related to vascular access sites or devices in patients on haemodialysis. Many of these infections are due to sepsis, primarily arising from the vascular access site.
STUDY DESIGN: Cross sectional.
PLACE OF STUDY: Department of Microbiology, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi.
PATIENTS AND METHODS: The study was conducted in Department of Microbiology, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi. during June 2005 to June 2006 to isolate the bacterial etiological agents in patients on haemodialysis. A total of 250 subjects irrespective of age and gender were included in this study. Intravenous double lumen (DL) catheter were collected from different hospital’s Nephrology Department e.g. Jinnah postgraduate Medical Centre, Kidney Centre and SIUT. Samples were inoculated on Chocolate agar and MacConkey agar and culture plates were incubated at 37°C for 24 hours. After 24 hours cultures were examined and gram stained. Antimicrobial sensitivity pattern of all the isolates was done by Kirby baur disc diffusion method.
RESULTS: The most common bacterial pathogens isolated were E.coli, Klebsiella, Proteus, Pseudomonas, Staph. epidermidis and Stap. aureus. Among these E.coli was the highest in number (50%) and Klebsiella the second most common bacteria (25%). Out of 250 cases 190 (76%) organisms were isolated. Most frequent organisms were isolated from subclavian vain (93%), internal jagular vein (4.5%) and 2.5% from femoral vein.
CONCLUSION: It has been concluded from this study that hemodialysis patients are more prone to infection irrespective of age or sex.
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