Posted in Volume 16 - Number 1 Suppl
AQUEELA AYAZ, SHAZIA SAEED, MIAN USMAN FAROOQ, MUHAMMAD LUQMAN ALI BAHOO, IFTIKHAR AHMAD, KASHIF HANIF
ABSTRACT | Full Text PDF
OBJECTIVE: To compare the maternal and neonatal outcomes in pregnancies with history of risk factors complicated by Gestational Diabetes Mellitus (GDM) which was controlled and pregnancies with similar risk factors without GDM.
MATERIALS AND METHODS: This prospective cohort study that included 420 pregnant women was conducted from 1st January 2004 to 31st December 2006 in the department of Obstetrics and Gynecology of Bahawal Victoria Hospital in Bahawalpur, Pakistan. The study subjects were divided into group A with positive oral glucose tolerance test (OGTT) 197(46.9%) and remaining (223) in group B. OGTT was done according to the National Diabetic Data Group. The GDM patients were treated with diet and insulin. Mann Whitney U test was applied to continuous data while Chi square test was applied to categorical data. P-value <0.05 was considered as significant.
RESULTS: No difference was found between group A and B regarding age, parity, BMI and hemoglobin. Cesarean section 48(24.4%) and pregnancy induced hypertension 41(20.8%) were significantly higher in group A than group B that is 27(12.1) and 28(12.6%) respectively (p-value <0.05). On the other hand, more babies were born as large for gestational age 31(15.7%) as compared to 16(7.2%) in group B (p-value<0.05). Similarly respiratory distress 36(18.3%) and neonatal ICU admission 68(34.5%) were higher in group A than group B that is 13(5.8%) and 31(13.9%) respectively (P-value<0.05).
CONCLUSION: Pregnancies with even controlled GDM are associated with higher frequency of adverse maternal and fetal outcomes as compared to pregnancies with similar high risk history.
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